| Primary Identifier | MGI:2179523 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 246256 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables IgE receptor activity and IgG receptor activity. Involved in several processes, including Fc receptor-mediated immune complex endocytosis; neutrophil activation; and positive regulation of bone resorption. Located in cell surface and plasma membrane. Is expressed in liver. Human ortholog(s) of this gene implicated in several diseases, including allergic disease (multiple); autoimmune disease (multiple); glomerulonephritis (multiple); graft-versus-host disease; and hematologic cancer (multiple). Orthologous to several human genes including FCGR3A (Fc gamma receptor IIIa). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased susceptibility to induced arthritis and nephrotoxic nephritis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
