| Primary Identifier | MGI:1353620 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 30925 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in natural killer cell differentiation and natural killer cell proliferation. Predicted to be located in plasma membrane. Predicted to be active in external side of plasma membrane. Orthologous to human SLAMF6 (SLAM family member 6). PHENOTYPE: Mice homozygous for one null allele show no overt phenotype. Mice homozygous for another null allele show impaired IL-4 production by CD4+ T cells, reduced inflammatory response to L. mexicana infection, high susceptibility to S. typhimurium infection, and defective neutrophil bactericidal activity. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
