Primary Identifier | MGI:1921998 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 74748 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables identical protein binding activity and signaling receptor activity. Involved in B-1 B cell lineage commitment and regulation of B cell differentiation. Acts upstream of or within several processes, including leukocyte chemotaxis involved in inflammatory response; negative regulation of leukocyte migration; and negative regulation of respiratory burst involved in inflammatory response. Predicted to be located in membrane. Orthologous to human SLAMF8 (SLAM family member 8). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased Nox2 activity in macrophage. [provided by MGI curators] |