| Primary Identifier | MGI:1346089 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 24012 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables GTPase activator activity. Involved in G protein-coupled receptor signaling pathway and regulation of postsynaptic membrane potential. Acts upstream of or within regulation of G protein-coupled receptor signaling pathway. Located in dendrite terminus; nucleus; and plasma membrane. Is active in several cellular components, including dendrite; glutamatergic synapse; and synaptic membrane. Is expressed in bone; foot mesenchyme; nervous system; pelvic girdle skeleton; and sensory organ. Orthologous to human RGS7 (regulator of G protein signaling 7). PHENOTYPE: Mice homozygous for a hypomorphic allele exhibit reduced exploration in a new environment, impaired glucose tolerance in males, and abnormal rod b-wave electrophysiology. Mice homozygous for a knock-out allele exhibit runting, delayed eye opening, and transient prolonged b-wave implicit time. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
