Primary Identifier | MGI:1338022 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 13603 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable 11-cis retinal binding activity; G protein-coupled photoreceptor activity; and all-trans retinal binding activity. Involved in positive regulation of D-glucose import; positive regulation of cellular respiration; and response to blue light. Predicted to be located in cytoplasm. Predicted to be active in photoreceptor outer segment and plasma membrane. Is expressed in eye and orbito-sphenoid. Orthologous to human OPN3 (opsin 3). PHENOTYPE: Mice homozygous for a null allele exhibit normal photoentrainment but impaired adaptive thermoregulation. Mice homozygous for a conditional allele activated in adipocytes exhibit blue-light sensitive impairment in adaptive thermoregulation. [provided by MGI curators] |