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Protein Coding Gene : Desi2 desumoylating isopeptidase 2
Primary Identifier  MGI:1926075 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  78825
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable deubiquitinase activity and long-chain fatty acyl-CoA hydrolase activity. Predicted to be involved in macromolecule depalmitoylation and proteolysis. Located in cytoplasm. Is expressed in several structures, including brain; genitourinary system; gut; muscle tissue; and spleen. Orthologous to human DESI2 (desumoylating isopeptidase 2).
PHENOTYPE: Mice homozygous for a knock-out mouse exhibit normal body size, body weight, brain size, brain weight and neuron apoptosis. [provided by MGI curators]
  • synonyms:
  • 5830417C01Rik,
  • Fam152a,
  • Desi2,
  • family with sequence similarity 152, member A,
  • Pppde1,
  • RIKEN cDNA 5830417C01 gene,
  • PPPDE peptidase domain containing 1,
  • desumoylating isopeptidase 2
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Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

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2 Involved In Mutations

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0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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