Primary Identifier | MGI:1916147 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 68897 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within several processes, including embryonic pattern specification; patched ligand maturation; and regionalization. Predicted to be active in membrane. Is expressed in several structures, including embryo ectoderm; foot bone; notochord; palatal shelf; and urinary system. Orthologous to human DISP1 (dispatched RND transporter family member 1). PHENOTYPE: Mice homozygous for targeted and chemically induced mutations exhibit a dorsalized neural tube, impaired heart looping, pericardial edema, large forelimbs, and abnormal head shape. [provided by MGI curators] |