Primary Identifier | MGI:102467 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 19250 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein tyrosine phosphatase activity; receptor tyrosine kinase binding activity; and transcription coregulator activity. Involved in lymphangiogenesis. Predicted to be located in nucleoplasm. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; musculoskeletal system; and sensory organ. Orthologous to human PTPN14 (protein tyrosine phosphatase non-receptor type 14). PHENOTYPE: Mice homozygous for a gene trap allele exhibit some postnatal growth retardation, decreased body weight, periorbital and limb edema, and lymphatic vessel hyperplasia. [provided by MGI curators] |