Primary Identifier | MGI:2444826 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 226841 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables actin binding activity and metallocarboxypeptidase activity. Involved in proteolysis. Acts upstream of or within labyrinthine layer blood vessel development; positive regulation of angiogenesis; and syncytium formation by plasma membrane fusion. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Is expressed in brain; cerebral cortex intermediate zone; cerebral cortex ventricular layer; cortical plate; and hippocampus. Orthologous to human VASH2 (vasohibin 2). PHENOTYPE: Homozygous null mice have defects in initiating angiogenesis in response to skin wounding. [provided by MGI curators] |