| Primary Identifier | MGI:2441706 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 215243 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein-macromolecule adaptor activity and zf-TRAF domain binding activity. Acts upstream of or within several processes, including antiviral innate immune response; cellular response to cytokine stimulus; and positive regulation of type I interferon production. Predicted to be located in Golgi membrane; endoplasmic reticulum membrane; and mitochondrial membrane. Predicted to be active in mitochondrion. Is expressed in several structures, including cerebral cortex; eye; foregut; limb segment; and vertebral axis musculature. Orthologous to human TRAF3IP3 (TRAF3 interacting protein 3). PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired single positive thymocyte development and increased gamma-delta T cell numbers. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
