| Primary Identifier | MGI:1316737 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 14373 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in positive regulation of cold-induced thermogenesis. Predicted to be active in mitochondrion. Is expressed in liver and trunk mesenchyme. Orthologous to human G0S2 (G0/G1 switch 2). PHENOTYPE: Homozygous null mice are lean, glucose tolerant and insulin sensitive, and show reduced liver triglyceride levels, enhanced lipolysis, reduced white fat cell size, resistance to diet-induced obesity and liver steatosis, increased oxygen consumption and thermogenesis, and enhanced cold tolerance. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
