| Primary Identifier | MGI:1914391 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 67141 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable anaphase-promoting complex binding activity; protein kinase binding activity; and ubiquitin ligase inhibitor activity. Involved in regulation of mitotic cell cycle. Acts upstream of or within several processes, including microtubule cytoskeleton organization; negative regulation of meiotic nuclear division; and oocyte maturation. Located in cytoplasm and meiotic spindle. Is expressed in several structures, including brain; early conceptus; gonad; metanephros; and spleen. Orthologous to human FBXO5 (F-box protein 5). PHENOTYPE: Mice homozygous for a null mutation display embryonic lethality before implantation, impaired embryogenesis, and mitotic abnormalities. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
