| Primary Identifier | MGI:1915094 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 67844 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including AP-1 adaptor complex binding activity; AP-3 adaptor complex binding activity; and BLOC-2 complex binding activity. Predicted to be involved in several processes, including endosome to melanosome transport; melanosome assembly; and phagosome maturation. Located in melanosome. Is expressed in duodenum; ileum; metanephros; prostate gland; and testis. Orthologous to human RAB32 (RAB32, member RAS oncogene family). PHENOTYPE: Homozygous dendritic cell-specific conditional knockout results in increased pathogen load in liver and spleen after bacterial infection. It also increases susceptibility to, and morbidity and mortality of, DSS-induced colitis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
