| Primary Identifier | MGI:2149955 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 94222 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and E-box binding activity. Acts upstream of or within negative regulation of transcription by RNA polymerase II; spinal cord motor neuron cell fate specification; and spinal cord motor neuron migration. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; future hindbrain; genitourinary system; inner ear; and skeletal muscle. Orthologous to human OLIG3 (oligodendrocyte transcription factor 3). PHENOTYPE: Homozygous mutant mice exhibit impaired development of class A neurons in the dorsal spinal cord, the alar plate, with reduced numbers of dI1 neurons and misspecified dI2 and dI3 neurons that assume the identity of class B neurons. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
