| Primary Identifier | MGI:3605069 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 237313 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables interleukin-20 binding activity. Acts upstream of or within cytokine-mediated signaling pathway; positive regulation of intrinsic apoptotic signaling pathway; and regulation of bone resorption. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in epididymis; eye; and ileum. Orthologous to human IL20RA (interleukin 20 receptor subunit alpha). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased bone mineral density, impaired osteoclast differentiation, and resistance to ovariectomized-inducced bone loss. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
