Primary Identifier | MGI:1923407 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 76157 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables UDP-glucose transmembrane transporter activity and protein-macromolecule adaptor activity. Involved in UDP-glucose transmembrane transport; platelet dense granule organization; and positive regulation of autophagy. Acts upstream of or within energy homeostasis and positive regulation of protein exit from endoplasmic reticulum. Located in early endosome and endoplasmic reticulum. Is active in early endosome membrane. Is expressed in midbrain mantle layer and thymus primordium. Orthologous to human SLC35D3 (solute carrier family 35 member D3). PHENOTYPE: Mice homozygous for a spontaneous mutation exhibit decreased platelet serotonin. [provided by MGI curators] |