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Protein Coding Gene : Bclaf1 BCL2-associated transcription factor 1
Primary Identifier  MGI:1917580 Organism  mouse, laboratory
Chromosome  10 NCBI Gene Number  72567
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable DNA binding activity and transcription coregulator activity. Acts upstream of or within cellular response to leukemia inhibitory factor. Predicted to be located in nuclear speck. Predicted to be part of mediator complex. Is expressed in several structures, including central nervous system; genitourinary system; retina; submandibular gland; and trachea. Orthologous to human BCLAF1 (BCL2 associated transcription factor 1).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit postnatal lethality, impaired lung development, and T cell and B cell homeostasis abnormalities. [provided by MGI curators]
  • synonyms:
  • MGI:1919817,
  • RIKEN cDNA 2700025J07 gene,
  • 2810454G14Rik,
  • RIKEN cDNA 5730534O06 gene,
  • RIKEN cDNA 2810454G14 gene,
  • 5730534O06Rik,
  • mKIAA0164,
  • 2610102K23Rik,
  • 2700025J07Rik,
  • BCL2-associated transcription factor 1,
  • MGI:2143607,
  • RIKEN cDNA 2610102K23 gene,
  • expressed sequence AI450190,
  • AI450190,
  • Bclaf1,
  • MGI:1914501,
  • MGI:2143868,
  • AW556225,
  • MGI:1917913,
  • expressed sequence AW556225
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