Primary Identifier | MGI:1917580 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 72567 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA binding activity and transcription coregulator activity. Acts upstream of or within cellular response to leukemia inhibitory factor. Predicted to be located in nuclear speck. Predicted to be part of mediator complex. Is expressed in several structures, including central nervous system; genitourinary system; retina; submandibular gland; and trachea. Orthologous to human BCLAF1 (BCL2 associated transcription factor 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit postnatal lethality, impaired lung development, and T cell and B cell homeostasis abnormalities. [provided by MGI curators] |