Primary Identifier | MGI:1923556 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 76306 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable monoamine:proton antiporter activity and polyamine:proton antiporter activity. Involved in spermidine transport and spermine transport. Located in secretory granule membrane. Is expressed in dorsal root ganglion and spinal cord. Orthologous to human SLC18B1 (solute carrier family 18 member B1). PHENOTYPE: Mice homozygous for a conditional allele ubiquitously activated exhibit reduced brain polyamine levels, impaired memory and altered response to addictive substances. [provided by MGI curators] |