Primary Identifier | MGI:2143628 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 237339 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including histone binding activity; identical protein binding activity; and methylation-dependent protein binding activity. Involved in regulation of ubiquitin-dependent protein catabolic process. Acts upstream of or within erythrocyte maturation; granulocyte differentiation; and macrophage differentiation. Located in nucleus. Is expressed in retina. Orthologous to human L3MBTL3 (L3MBTL histone methyl-lysine binding protein 3). PHENOTYPE: Mice homozygous for a null mutation die between E17.5 ? 19.5 due to disturbed erythropoiesis which result in anemia. [provided by MGI curators] |