| Primary Identifier | MGI:2444847 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 211329 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable nuclear receptor binding activity and nuclear receptor coactivator activity. Acts upstream of or within negative regulation of cellular response to oxidative stress and negative regulation of peptidyl-cysteine S-nitrosylation. Predicted to be active in nucleus. Is expressed in several structures, including adipose tissue; brain; genitourinary system; gut; and hemolymphoid system gland. Orthologous to human NCOA7 (nuclear receptor coactivator 7). PHENOTYPE: Homozygous knockout affects lysosomal function in cortical neurons and in kidneys, leading to alkalinization of neuron somas and of urine. It also affects neuronal development, leading to anxiety and social impairments. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
