| Primary Identifier | MGI:1924007 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 76757 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein-macromolecule adaptor activity. Involved in heart contraction. Acts upstream of or within establishment of localization in cell; release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; and response to bacterium. Predicted to be located in cytosol; nucleoplasm; and sarcoplasmic reticulum. Predicted to be part of calcium channel complex and junctional membrane complex. Predicted to be active in junctional sarcoplasmic reticulum membrane and plasma membrane. Is expressed in embryo and heart. Human ortholog(s) of this gene implicated in catecholaminergic polymorphic ventricular tachycardia and catecholaminergic polymorphic ventricular tachycardia 5. Orthologous to human TRDN (triadin). PHENOTYPE: Mice homozygous for a null allele exhibit a loss of transverse orientation of triads within skeletal muscle cells. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
