| Primary Identifier | MGI:2385847 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 171580 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables several functions, including FAD binding activity; actin binding activity; and enzyme binding activity. Involved in several processes, including actin filament depolymerization; negative regulation of protein metabolic process; and sulfur oxidation. Located in hippocampal mossy fiber expansion. Orthologous to human MICAL1 (microtubule associated monooxygenase, calponin and LIM domain containing 1). PHENOTYPE: Homozygous KO leads to increased mortality after cardiac stress. Mice show impaired lamina-specific targeting of mossy fibre axons onto CA3 pyramidal neurons in the developing hippocampus. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
