Primary Identifier | MGI:3584032 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 380669 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable mRNA binding activity and sequence-specific double-stranded DNA binding activity. Predicted to be involved in RNA metabolic process and positive regulation of macromolecule metabolic process. Predicted to be located in cytosol; nucleolus; and nucleoplasm. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and lumbar dorsal root ganglion. Used to study neuroblastoma. Orthologous to human LIN28B (lin-28 homolog B). PHENOTYPE: Mice homozygous for a knock-out allele exhibit postnatal dwarfism in male, but not female, mice. [provided by MGI curators] |