| Primary Identifier | MGI:2429498 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 210198 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables G protein-coupled peptide receptor activity. Involved in several processes, including adenylate cyclase-activating G protein-coupled receptor signaling pathway; positive regulation of insulin secretion involved in cellular response to glucose stimulus; and regulation of testosterone biosynthetic process. Is active in plasma membrane. Is expressed in several structures, including femur; liver; male reproductive gland or organ; musculature; and spleen. Orthologous to human GPRC6A (G protein-coupled receptor class C group 6 member A). PHENOTYPE: Mice homozygous for a knock-out allele show a metabolic syndrome characterized by impaired bone mineralization, increased fat mass, abnormal renal handling of calcium and phosphorus, fatty liver, glucose intolerance, testicular feminization and abnormal steroidogenesis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
