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Protein Coding Gene : Vgll2 vestigial like family member 2

Primary Identifier  MGI:2447460 Organism  mouse, laboratory
Chromosome  10 NCBI Gene Number  215031
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables transcription coactivator activity. Acts upstream of or within positive regulation of transcription by RNA polymerase II and skeletal muscle tissue development. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; branchial arch; limb bud; skeletal muscle; and somite. Orthologous to human VGLL2 (vestigial like family member 2).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit abnormal skeletal muscle fiber type ratio and impaired exercise endurance. [provided by MGI curators]
  • synonyms:
  • MGI:2443345,
  • Vgll2,
  • vestigial like family member 2,
  • RIKEN cDNA C130057C21 gene,
  • C130057C21Rik,
  • VITO-1,
  • Vgl-2,
  • Vito1

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For