Primary Identifier | MGI:2447460 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 215031 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables transcription coactivator activity. Acts upstream of or within positive regulation of transcription by RNA polymerase II and skeletal muscle tissue development. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; branchial arch; limb bud; skeletal muscle; and somite. Orthologous to human VGLL2 (vestigial like family member 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit abnormal skeletal muscle fiber type ratio and impaired exercise endurance. [provided by MGI curators] |