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Protein Coding Gene : Unc5b unc-5 netrin receptor B
Primary Identifier  MGI:894703 Organism  mouse, laboratory
Chromosome  10 NCBI Gene Number  107449
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable netrin receptor activity. Acts upstream of or within anterior/posterior axon guidance. Predicted to be located in membrane raft. Is expressed in several structures, including brain; forelimb; ganglia; limb bud; and sensory organ. Orthologous to human UNC5B (unc-5 netrin receptor B).
PHENOTYPE: Mice homozygous for a severely hypomorphic allele exhibit background sensitive lethality during organogenesis. [provided by MGI curators]
  • synonyms:
  • Unc5b,
  • D10Bwg0792e,
  • RIKEN cDNA 6330415E02 gene,
  • MGI:106392,
  • Unc5h2,
  • unc5 homolog (C. elegans) 2,
  • unc-5 netrin receptor B,
  • MGI:1924103,
  • MGD-MRK-34085,
  • DNA segment, Chr 10, Brigham & Women's Genetics 0792 expressed,
  • 6330415E02Rik
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