| Primary Identifier | MGI:1351623 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 27355 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein tyrosine phosphatase activity. Predicted to be located in cytosol. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including cardiovascular system; central nervous system; jaw; lung; and urinary system. Orthologous to human PALD1 (phosphatase domain containing paladin 1). PHENOTYPE: Female, but not male, mice homozygous for a knock-out allele exhibit an emphysema-like phenotype associated with increased alveolar air spaces, impaired lung function, and increased lung endothelial cell apoptosis and proliferation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
