Primary Identifier | MGI:1919017 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 71767 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables serine-type endopeptidase activity. Predicted to be involved in protein processing and regulation of fatty acid beta-oxidation. Predicted to be located in peroxisomal matrix. Predicted to be active in peroxisome. Orthologous to human TYSND1 (trypsin like peroxisomal matrix peptidase 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit male infertility with globozoospermia, hypoactivity, absence acrosomal cap, indicators of liver damage, abnormal hepatocyte peroxisomes and autophagosomes and enlarged, beige livers. [provided by MGI curators] |