Primary Identifier | MGI:97756 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 19073 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable collagen binding activity. Involved in negative regulation of cytokine production; protein localization to secretory granule; and protein processing. Located in mast cell granule. Is expressed in several structures, including autopod; central nervous system; liver; lower jaw; and thymus primordium. Orthologous to human SRGN (serglycin). PHENOTYPE: Mice homozygous for disruptions in this gene lack peritoneal mast cells. [provided by MGI curators] |