Primary Identifier | MGI:1914595 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 67345 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ubiquitin protein ligase activity. Involved in spermatogenesis. Predicted to be located in cytosol and fibrillar center. Predicted to be active in cytoplasm. Orthologous to human HERC4 (HECT and RLD domain containing E3 ubiquitin protein ligase 4). PHENOTYPE: Mice homozygous for a gene-trapped allele display reduced male fertility associated with a high percentage of angulated sperm tails and impaired sperm motility. [provided by MGI curators] |