Primary Identifier | MGI:2143676 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 216049 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein homodimerization activity. Involved in several processes, including cerebellar molecular layer morphogenesis; dendrite morphogenesis; and positive regulation of oligodendrocyte differentiation. Predicted to be located in centrosome. Is expressed in several structures, including cerebral cortex; lens; liver; spleen; and testis. Human ortholog(s) of this gene implicated in uric acid nephrolithiasis. Orthologous to human ZNF365 (zinc finger protein 365). PHENOTYPE: Mice homozygous for a knock-out allele exhibit abnormal cortical basket cells in the somatosensory cortices, delayed myelination in the corpus callosum during the early postnatal period, and an increase in immature oligodendrocytes. [provided by MGI curators] |