Primary Identifier | MGI:2175912 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 71371 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable transcription cis-regulatory region binding activity and transcription coactivator activity. Involved in adipose tissue development. Acts upstream of or within several processes, including cellular response to leukemia inhibitory factor; face morphogenesis; and gonad development. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; embryo ectoderm; embryo mesenchyme; genitourinary system; and sensory organ. Orthologous to human ARID5B (AT-rich interaction domain 5B). PHENOTYPE: Mice homozygous for disruptions in this gene experience a high level of mortality perinatally or earlier. Growth rates are low and mice remain small throughout live. There are abnormalities in various organ systems as well as the reproductive system. Fertility is reduced. [provided by MGI curators] |