Primary Identifier | MGI:1261855 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 52637 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including 2 iron, 2 sulfur cluster binding activity; L-cysteine transaminase activity; and protein homodimerization activity. Acts upstream of or within regulation of cellular respiration. Located in mitochondrial outer membrane. Is expressed in several structures, including ganglia; genitourinary system; heart; immune system; and liver. Orthologous to human CISD1 (CDGSH iron sulfur domain 1). PHENOTYPE: Mice homozygous for a null allele exhibit reduced oxidative capacity. [provided by MGI curators] |