Primary Identifier | MGI:1916968 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 69718 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables inositol-1,4,5,6-tetrakisphosphate 3-kinase activity and inositol-1,4,5-trisphosphate 3-kinase activity. Acts upstream of or within inositol phosphate biosynthetic process and neural tube formation. Predicted to be located in nucleoplasm. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including branchial arch; hindlimb ridge; nervous system; retina nuclear layer; and trunk somite. Orthologous to human IPMK (inositol polyphosphate multikinase). PHENOTYPE: Homozygous null mice display embryonic lethality, reduced embryo size, delayed embryonic development, failure of chorioallantoic fusion and embryo turning, and a kinked and open neural tube. [provided by MGI curators] |