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Protein Coding Gene : Ipmk inositol polyphosphate multikinase

Primary Identifier  MGI:1916968 Organism  mouse, laboratory
Chromosome  10 NCBI Gene Number  69718
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables inositol-1,4,5,6-tetrakisphosphate 3-kinase activity and inositol-1,4,5-trisphosphate 3-kinase activity. Acts upstream of or within inositol phosphate biosynthetic process and neural tube formation. Predicted to be located in nucleoplasm. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including branchial arch; hindlimb ridge; nervous system; retina nuclear layer; and trunk somite. Orthologous to human IPMK (inositol polyphosphate multikinase).
PHENOTYPE: Homozygous null mice display embryonic lethality, reduced embryo size, delayed embryonic development, failure of chorioallantoic fusion and embryo turning, and a kinked and open neural tube. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 2410017C19 gene,
  • AA408208,
  • expressed sequence AA408208,
  • Ipmk,
  • 2410017C19Rik,
  • MGI:2143463,
  • inositol polyphosphate multikinase

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

3 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For