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Protein Coding Gene : Mmp11 matrix metallopeptidase 11
Primary Identifier  MGI:97008 Organism  mouse, laboratory
Chromosome  10 NCBI Gene Number  17385
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables metallopeptidase activity. Acts upstream of or within collagen catabolic process; extracellular matrix organization; and negative regulation of fat cell differentiation. Predicted to be located in extracellular matrix. Predicted to be active in extracellular space. Is expressed in several structures, including extraembryonic component; floor plate; limb interdigital region; musculoskeletal system; and reproductive system. Orthologous to human MMP11 (matrix metallopeptidase 11).
PHENOTYPE: Homozygous null mice exhibit a decreased incidence of DMBA-induced carcinomas. [provided by MGI curators]
  • synonyms:
  • MGD-MRK-12278,
  • stromelysin 3,
  • Stmy3,
  • Mmp11,
  • ST3,
  • stromelysis 3,
  • matrix metallopeptidase 11,
  • MGD-MRK-14628
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Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For





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