| Primary Identifier | MGI:1316652 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 15468 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables beta-catenin binding activity; histone H3 methyltransferase activity; and protein-arginine N-methyltransferase activity. Involved in negative regulation of G1/S transition of mitotic cell cycle; regulation of DNA-templated transcription; and response to hypoxia. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human PRMT2 (protein arginine methyltransferase 2). PHENOTYPE: Mice homozygous for a knock-out allele display a hyperplastic response to vascular injury while mutant mouse embryonic fibroblasts show an earlier S phase entry following release of serum starvation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
