| Primary Identifier | MGI:1923823 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 76573 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein kinase A regulatory subunit binding activity. Acts upstream of or within several processes, including actin polymerization or depolymerization; positive regulation of cAMP-dependent protein kinase activity; and positive regulation of cAMP/PKA signal transduction. Located in centrosome and sperm head-tail coupling apparatus. Is expressed in several structures, including alimentary system; genitourinary system; heart; nervous system; and sensory organ. Orthologous to human SPATC1L (spermatogenesis and centriole associated 1 like). PHENOTYPE: Male mice homozygous for a null mutation are infertile with acephalic sperm and detached sperm tails. Male mice heterozygous for a null mutation display reduced fertility with similar sperm abnormalities. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
