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Protein Coding Gene : Madcam1 mucosal vascular addressin cell adhesion molecule 1
Primary Identifier  MGI:103579 Organism  mouse, laboratory
Chromosome  10 NCBI Gene Number  17123
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable integrin binding activity involved in cell-matrix adhesion. Acts upstream of or within keratinocyte differentiation and leukocyte migration. Predicted to be located in membrane. Is expressed in eyelid; hair follicle; and hemolymphoid system. Orthologous to human MADCAM1 (mucosal vascular addressin cell adhesion molecule 1).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit small Peyer's patches and decreased homing of IgA-secreting plasma cells in the lamina propria. [provided by MGI curators]
  • synonyms:
  • expressed sequence AV211525,
  • MGD-MRK-24464,
  • MGC:35998,
  • Madcam1,
  • mucosal vascular addressin cell adhesion molecule 1,
  • AV211525,
  • MGI:2143785
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0 Canonical

0 CDSs

0 Exons

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1 Involved In Mutations

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0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

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Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

5 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

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Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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1 Driver For





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