| Primary Identifier | MGI:99549 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 16904 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables endopeptidase activity. Acts upstream of or within T cell mediated cytotoxicity. Predicted to be active in extracellular space. Is expressed in retina. Orthologous to human GZMM (granzyme M). PHENOTYPE: Mice homozygous for a knock-in allele display normal immune homeostasis, normal NK cell cytotoxicity and a normal response to ectromelia virus infection, but show a transient but significant increase in susceptibility to infection with the murine cytomegalovirus. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
