Primary Identifier | MGI:1917544 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 70294 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables epidermal growth factor receptor binding activity and ubiquitin protein ligase activity. Involved in protein K48-linked ubiquitination and protein K63-linked ubiquitination. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in cytoplasm. Orthologous to human RNF126 (ring finger protein 126). PHENOTYPE: Homozygous null mice show partial prenatal lethality and shorter survival time and increased cellular apoptosis following irradiation exposure. [provided by MGI curators] |