| Primary Identifier | MGI:1890391 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 83554 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables activin binding activity. Acts upstream of or within negative regulation of BMP signaling pathway. Located in extracellular space. Is expressed in several structures, including brain; foregut; limb; male reproductive gland or organ; and thymus. Orthologous to human FSTL3 (follistatin like 3). PHENOTYPE: Adult mice homozygous for a knock-out allele display increased pancreatic islet number and size, beta cell hyperplasia, hepatic steatosis, increased heart weight, mild hypertension, and alterations in glucose homeostasis and fat distribution. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
