Primary Identifier | MGI:1920356 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 73106 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable heparin binding activity and serine-type endopeptidase activity. Predicted to be involved in protein maturation and proteolysis. Predicted to be located in azurophil granule lumen. Predicted to be active in extracellular space. Orthologous to human PRSS57 (serine protease 57). PHENOTYPE: Mice homozygous for a null allele display reduced levels of histamine and serotonin in mast cells resulting in defects in mast cell function. [provided by MGI curators] |