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Protein Coding Gene : Prss57 serine protease 57

Primary Identifier  MGI:1920356 Organism  mouse, laboratory
Chromosome  10 NCBI Gene Number  73106
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable heparin binding activity and serine-type endopeptidase activity. Predicted to be involved in protein maturation and proteolysis. Predicted to be located in azurophil granule lumen. Predicted to be active in extracellular space. Orthologous to human PRSS57 (serine protease 57).
PHENOTYPE: Mice homozygous for a null allele display reduced levels of histamine and serotonin in mast cells resulting in defects in mast cell function. [provided by MGI curators]
  • synonyms:
  • Prss57,
  • UNQ782,
  • protease, serine-like 1,
  • 2900092M14Rik,
  • RIKEN cDNA 2900092M14 gene,
  • GLGL782,
  • serine protease 57,
  • Prssl1

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For