Primary Identifier | MGI:1328360 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 13496 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables several functions, including chromatin binding activity; identical protein binding activity; and transcription coregulator activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within regulation of DNA-templated transcription. Located in nucleus. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and immune system. Orthologous to human ARID3A (AT-rich interaction domain 3A). PHENOTYPE: Mice homozygous for a knock-out allele exhibit embryonic lethality between E11.5 and E13.5 due to impaired erythropoiesis. [provided by MGI curators] |