| Primary Identifier | MGI:2448490 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 216161 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable chromatin DNA binding activity and histone binding activity. Involved in several processes, including cellular response to cytokine stimulus; cellular response to lipopolysaccharide; and macrophage activation involved in immune response. Acts upstream of or within several processes, including bone mineralization; bone trabecula morphogenesis; and osteoclast fusion. Predicted to be active in nucleus. Is expressed in cerebral cortex ventricular layer; cortical plate; submandibular gland primordium; and vibrissa. Orthologous to human SBNO2 (strawberry notch homolog 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired osteoclast fusion, impaired osteoblastogenesis, osteopetrosis, increased bone mass, and decreased body weight. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
