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Protein Coding Gene : Cirbp cold inducible RNA binding protein

Primary Identifier  MGI:893588 Organism  mouse, laboratory
Chromosome  10 NCBI Gene Number  12696
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables poly(U) RNA binding activity and translation repressor activity. Involved in stress granule assembly. Acts upstream of or within cellular response to cold; negative regulation of cell growth; and regulation of cell cycle G1/S phase transition. Located in cytoplasmic stress granule and nucleoplasm. Is expressed in several structures, including central nervous system; olfactory epithelium; and retina. Orthologous to human CIRBP (cold inducible RNA binding protein).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired spermatogonia proliferation. [provided by MGI curators]
  • synonyms:
  • Cirp,
  • Cirbp,
  • expressed sequence R74941,
  • R74941,
  • MGI:2143957,
  • cold inducible RNA binding protein

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For