Primary Identifier | MGI:1917498 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 70248 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables RNA stem-loop binding activity. Acts upstream of or within several processes, including fibroblast proliferation; maternal placenta development; and positive regulation of mRNA splicing, via spliceosome. Located in cytoplasm and male germ cell nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human DAZAP1 (DAZ associated protein 1). PHENOTYPE: Homozygotes for a null allele show partial lethality during fetal growth through weaning, growth retardation, spermatogenic arrest, and premature death. Homozygotes for a hypomorphic allele live longer but are small and sterile and display small gonads, spermatogenic arrest, and abnormal pregnancy. [provided by MGI curators] |