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Protein Coding Gene : Mbd3 methyl-CpG binding domain protein 3
Primary Identifier  MGI:1333812 Organism  mouse, laboratory
Chromosome  10 NCBI Gene Number  17192
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0)

Enables DNA binding activity. Acts upstream of or within in utero embryonic development and tissue development. Located in cytoplasm; heterochromatin; and nucleus. Part of NuRD complex. Is expressed in several structures, including 4-8 cell stage conceptus; blastocyst-stage conceptus; central nervous system; early embryo; and oocyte. Orthologous to human MBD3 (methyl-CpG binding domain protein 3).
PHENOTYPE: Mice homozygous for disruptions in this gene experience deficiencies as embryos around implantation and die before birth. [provided by MGI curators]
  • synonyms:
  • MGI:2143734,
  • MGI:2143531,
  • methyl-CpG binding domain protein 3,
  • expressed sequence AU019209,
  • Mbd3,
  • AI181826,
  • AU019209,
  • expressed sequence AI181826
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Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

21 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For





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