Primary Identifier | MGI:1333812 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 17192 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA binding activity. Acts upstream of or within in utero embryonic development and tissue development. Located in cytoplasm; heterochromatin; and nucleus. Part of NuRD complex. Is expressed in several structures, including central nervous system; early conceptus; oocyte; and retina. Orthologous to human MBD3 (methyl-CpG binding domain protein 3). PHENOTYPE: Mice homozygous for disruptions in this gene experience deficiencies as embryos around implantation and die before birth. [provided by MGI curators] |